Answer
It can reduce bone mineral density, and kidney tubule injury may rarely cause bone softening, pain or fractures. Persistent bone pain should be assessed.
Sources for this answer
- Tenofovir disoproxil Milparm 245mg film-coated tablets — Current selected SmPCemc · Summary of Product Characteristics
General medicine information. Follow the instructions for your own medicine and speak to a pharmacist or clinician about your individual circumstances.