Answer
Yes. After glucose is metabolised, the fluid can become physiologically hypotonic, particularly with increased vasopressin activity or impaired water excretion.
Sources for this answer
- Glucose Intravenous Infusion BP 20% w/v — Current selected SmPCemc · Summary of Product Characteristics
- Glucose 40% w/v Concentrate for solution for infusion — Current selected SmPCemc · Summary of Product Characteristics