Answer
Severe kidney disease or renal failure is a contraindication. Moderate or other significant renal impairment requires professional assessment because both components are mainly eliminated through the kidneys.
Sources for this answer
- Benadryl Allergy Relief Plus Decongestant Capsules — Current selected SmPCemc · Summary of Product Characteristics
General medicine information. Follow the instructions for your own medicine and speak to a pharmacist or clinician about your individual circumstances.