Answer
Ibuprofen can reduce pemetrexed clearance and increase toxicity, especially when kidney function is impaired. Ask the oncology team before taking it or another NSAID.
Sources for this answer
- Pemetrexed SUN 6.5 mg/ml solution for infusion — Current selected SmPCemc · Summary of Product Characteristics
General medicine information. Follow the instructions for your own medicine and speak to a pharmacist or clinician about your individual circumstances.