Answer
Usually not. Both are NSAIDs, and combining them increases the risk of gastrointestinal bleeding, kidney injury and other adverse effects unless specifically supervised.
Sources for this answer
- Mefenamic Acid 500 mg Tabletsemc · SmPC Current selected SmPC · Version 3
- Mefenamic Acid 50 mg/5 ml Suspensionemc · SmPC Current selected SmPC · Version 3