Answer
It is best to avoid alcohol because both alcohol and isotretinoin can affect the liver, and isotretinoin can raise blood fats.
Sources for this answer
- NHSNHS · NHS medicine guidance
- Isotretinoin 5 mg capsules — Current selected SmPCemc · Summary of Product Characteristics
General medicine information. Follow the instructions for your own medicine and speak to a pharmacist or clinician about your individual circumstances.