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Medicines hepatitis b vaccine (rDNA)Question & answer

hepatitis b vaccine (rDNA) · Medicine question

Can hepatitis b vaccine (rDNA) cause hepatitis B?

iatroX medicinesPublished 20 August 2026Reviewed 20 August 2026

The answer

Answer

No. It contains recombinant surface antigen rather than infectious hepatitis B virus.

Sources for this answer

NHSNHS · NHS medicine guidance
Engerix B 20 micrograms/1 ml Suspension for injection in pre-filled syringe (Adult and Paediatric)emc · SmPC Current selected SmPC · Version 20

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hepatitis b vaccine (rDNA)

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