Answer
Yes—Gazyvaro (obinutuzumab) can worsen pre-existing heart disease in chronic lymphocytic leukaemia or follicular lymphoma, with arrhythmias, angina, acute coronary syndrome, myocardial infarction or heart failure, potentially fatal and infusion-related; patients require close monitoring and cautious hydration to prevent fluid overload.
Sources for this answer
- Gazyvaro 1,000 mg concentrate for solution for infusionRoche Products Limited · emc · SmPC §4.4 Special warnings and precautions for use · Version 22Document updated
Sources checked