Answer
Yes. When used alone in mixed epilepsy, it may increase generalised tonic-clonic seizure frequency, so seizure classification and specialist review are important.
Sources for this answer
- Ethosuximide 250 mg capsules, soft Epesri 250 mg capsules, soft — Current selected SmPCemc · Summary of Product Characteristics
- Emeside 250 mg/5 ml Syrup / Ethosuximide Essential Generics 250 mg/5 ml Syrup — Current selected SmPCemc · Summary of Product Characteristics
General medicine information. Follow the instructions for your own medicine and speak to a pharmacist or clinician about your individual circumstances.