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Medicines DoxycyclineQuestion & answer

Doxycycline · Medicine question

Can doxycycline cause Clostridium difficile-associated diarrhoea?

iatroX medicinesPublished 8 November 2026

The answer

Answer

Yes, Clostridium difficile-associated diarrhoea has been reported with doxycycline and may range from mild diarrhoea to fatal colitis.

Sources for this answer

Vibramycin-D Dispersible Tablets 100mgPfizer Limited · emc · SmPC §4.4 Special warnings and precautions for use · Version 13Document updated 17 October 2025

Sources checked 8 November 2026

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Doxycycline

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