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Medicines daratumumabQuestion & answer

daratumumab · Medicine question

Can daratumumab (Darzalex) infusion cause serious or fatal infections?

iatroX medicinesPublished 8 November 2026

The answer

Answer

Yes, daratumumab (Darzalex) infusion can cause serious, life-threatening or fatal infections.

Sources for this answer

DARZALEX 20 mg/mL concentrate for solution for infusionJanssen-Cilag Ltd (a Johnson & Johnson Company) · emc · SmPC §4.4 Special warnings and precautions for use · Version 34Document updated 30 March 2026

Sources checked 8 November 2026

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How much sorbitol is present in the 5 mL and 20 mL vials of Darzalex daratumumab concentrate for infusion?Is daratumumab (Darzalex) infusion recommended during pregnancy?Is daratumumab (Darzalex) infusion recommended for children under 18 years?Which adults with relapsed and refractory multiple myeloma are eligible for daratumumab (Darzalex) infusion as monotherapy?Who should administer daratumumab (Darzalex) infusion, and what emergency facilities must be available?

daratumumab

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