Answer
Yes. COX-2 selectivity does not remove the risk of gastrointestinal ulceration, bleeding or perforation, especially with aspirin, anticoagulants or previous ulcer disease.
Sources for this answer
- Celecoxib 100mg Capsules — Current selected SmPCemc · Summary of Product Characteristics
- UK GovernmentUK Government · Reputable Web
General medicine information. Follow the instructions for your own medicine and speak to a pharmacist or clinician about your individual circumstances.