Answer
Yes. Serious hypersensitivity has been reported several years after treatment began, so appropriate safeguards are required for every infusion.
Sources for this answer
- Elaprase 2 mg/ml concentrate for solution for infusion — Current selected SmPCemc · Summary of Product Characteristics
- PubMedPubMed · Reputable Web
General medicine information. Follow the instructions for your own medicine and speak to a pharmacist or clinician about your individual circumstances.