alprostadil · Medicine question

Can alprostadil be used with sildenafil or tadalafil?

Name: Can alprostadil be used with sildenafil or tadalafil?
Published: 2026-08-18T15:59:06.801Z

iatroX medicinesPublished 18 August 2026Reviewed 18 August 2026

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Selected product information advises against combining erectile-dysfunction alprostadil with PDE5 inhibitors because hypotension or prolonged erection may occur.

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Alprostadil 10 micrograms powder for solution for injectionemc · SmPC Current selected SmPC · Version 1
Vitaros 3 mg/g creamemc · SmPC Current selected SmPC · Version 2

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