Answer
After oral administration of hydrochlorothiazide + losartan, losartan reaches its mean peak plasma concentration in 1 hour and its active metabolite in 3–4 hours.
Sources for this answer
- Cozaar - Comp 50/12.5mg, 100/12.5mg and 100/25mg Film-Coated TabletsOrganon Pharma (UK) Limited · emc · SmPC §5.2 Pharmacokinetic properties · Version 28Document updated
Sources checked