clinical q&a library
Explore a database of clinical questions answered by iatroX, referencing established clinical guidelines, SmPCs, and peer-reviewed literature.
What are the indications for referring a patient with suspected porphyria to a specialist clinic?
Indications for referring a patient with suspected porphyria to a specialist clinic include clinical suspicion based on characteristic sympt...
How should I manage a patient with porphyria who presents with acute abdominal pain and is at risk of an attack?
Management of a patient with porphyria presenting with acute abdominal pain and at risk of an attack involves prompt recognition and supportive care ...
Which laboratory tests are most useful for confirming a diagnosis of acute porphyria in primary care settings?
The most useful laboratory tests for confirming a diagnosis of acute porphyria in primary care are the measurement of urinary porphobilinogen (PBG) a...
What are the key clinical features that suggest a diagnosis of porphyria in a patient presenting with abdominal pain and neurological symptoms?
Key clinical features suggesting porphyria in a patient with abdominal pain and neurological symptoms include:Severe, un...
What follow-up measures should I implement after deprescribing to monitor patient outcomes and medication adherence?
After deprescribing, follow-up measures should include offering extra, unscheduled reviews when needed, especially if the patient reports ad...
How do I involve patients and their families in the decision-making process regarding deprescribing?
Involving patients and their families in deprescribing decisions involves several key steps:Offer the opportunity for in...
What are the recommended strategies for safely deprescribing medications in older adults?
Safe deprescribing of medications in older adults involves a patient-centred, gradual, and closely monitored approach to minimise withdrawal symptoms and adv...
How can I effectively assess the appropriateness of a patient's current medication regimen before considering deprescribing?
To effectively assess the appropriateness of a patient's current medication regimen before considering deprescribing, conduct a structured medication review ...
What criteria should I use to identify patients at risk of polypharmacy in my practice?
Criteria to identify patients at risk of polypharmacy in your practice include:Adults prescribed 15 or more regular medicines, a...
What lifestyle modifications should I advise to patients with polycythaemia to reduce cardiovascular risks?
Advise patients with polycythaemia to adopt lifestyle modifications aimed at reducing cardiovascular risk, including:Healthy eating:...
What are the recommended follow-up protocols for patients diagnosed with polycythaemia vera?
Recommended follow-up protocols for patients diagnosed with polycythaemia vera (PV) include regular clinical assessment and laboratory monitoring to ...
What follow-up strategies should be implemented for patients treated for aspergillosis to monitor for recurrence or complications?
Follow-up strategies for patients treated for aspergillosis should include:Regular clinical assessment to monitor symptoms and d...
When should I consider referring a patient with suspected invasive aspergillosis to a specialist?
Consider referring a patient with suspected invasive aspergillosis to a specialist immediately if they are immunocompromised, particularly if they ar...
What are the recommended first-line treatment options for patients diagnosed with chronic pulmonary aspergillosis?
For patients diagnosed with chronic pulmonary aspergillosis (CPA), the recommended first-line treatment is sustained antifungal therapy aimed at suppressing ...
Which diagnostic tests are most effective for confirming a diagnosis of aspergillosis in patients with respiratory symptoms?
For confirming a diagnosis of aspergillosis in patients presenting with respiratory symptoms, the most effective diagnostic approach combines clinical assess...
What are the key clinical features that differentiate invasive aspergillosis from chronic pulmonary aspergillosis in a primary care setting?
Invasive aspergillosis (IA) typically presents acutely with systemic and respiratory symptoms such as fever, pleuritic chest pain, haemoptys...
What are the recommended first-line treatments for a patient diagnosed with Polyarteritis Nodosa?
The recommended first-line treatment for Polyarteritis Nodosa (PAN) involves immunosuppressive therapy primarily with high-dose glucocorticoids combi...
What are the key clinical features that suggest a diagnosis of Polyarteritis Nodosa in a patient presenting with systemic symptoms?
Key clinical features suggesting a diagnosis of Polyarteritis Nodosa (PAN) in a patient with systemic symptoms include:C...
What vaccination recommendations should I provide to patients with a history of polio to prevent future infections?
Patients with a history of polio should be advised to maintain up-to-date poliovirus immunisation according to the UK routine immunisation schedule to preven...