clinical q&a library

Explore a database of clinical questions answered by iatroX, referencing established clinical guidelines, SmPCs, and peer-reviewed literature.

What are the causes and evidence-based treatment options for scalp psoriasis in

Cause and triggersScalp psoriasis is a manifestation of psoriasis, a systemic immune-mediated inflammatory skin disease with a chroni...

9 Aug 2026View Answer

<p>In a patient with several tumours in different parts of the body, what is

Most appropriate primary-care approach: treat this as malignancy of undefined primary origin (MUO)—metastatic malignancy id...

8 Aug 2026View Answer

What are the potential consequences and health outcomes of untreated chronic

Untreated CIDP can cause progressive and potentially irreversible peripheral nerve disability. The available evidence specifically supports ...

6 Aug 2026View Answer

Compare SSRI medication in these side effects: somnolence Fatigue or reduced

Evidence-limited comparison: The supplied UK sources provide adverse-effect frequencies only for fluoxetine and sertraline; they do not prov...

5 Aug 2026View Answer

What initial tests should be performed in primary care to determine whether

Initial primary-care work-upRepeat serum potassium at an interval guided by clinical judgement to exclude a spurious result and ...

5 Aug 2026View Answer

How should low potassium (hypokalaemia) be interpreted when considering dietary

Interpretation in primary care: Hypokalaemia is serum potassium below 3.5 mmol/L; classify it as mild (3.0–3.4 mmol/L), moderate (2.5–2.9 mm...

5 Aug 2026View Answer

<p>In adults, what is the clinical definition, diagnostic criteria, and

Clinical definitionMixed hyperlipidaemia (mixed dyslipidaemia) is a lipid-pattern diagnosis in which both cholesterol-containing athe...

5 Aug 2026View Answer

What is the recommended management of primary insomnia in adults in primary

Assessment and first steps: Confirm insomnia as difficulty initiating or maintaining sleep, or poor sleep quality, despite adequate opportun...

2 Aug 2026View Answer

What are the clinical benefits of cognitive behavioural therapy for insomnia

CBT-I is the preferred first-line treatment for adults with chronic insomnia because its benefits persist after treatment ends, whereas pharmacologic...

30 Jul 2026View Answer

go through nice guidance to suggest a protocol for doing a mental health care

Primary-care mental health care-plan protocolDevelop the mental healthcare plan collaboratively with the person and, where possi...

30 Jul 2026View Answer

What is the step-by-step management pathway for hypokalaemia in primary care,

Definitions and immediate triage: Hypokalaemia is serum potassium below 3.5 mmol/L; mild is 3.0–3.4 mmol/L, moderate is 2.5–2.9 mmol/L, and ...

27 Jul 2026View Answer

Are there evidence-based clinical studies supporting the use of colchicine for

Yes. Randomised trials and meta-analyses support low-dose colchicine as an adjunct to standard secondary prevention for selected patients wi...

26 Jul 2026View Answer

What does NICE guidance define as calcium-channel blocker intolerance in

NICE definition: NICE NG136 does not provide a formal diagnostic definition, severity threshold, or required duration for calcium-channel bl...

25 Jul 2026View Answer

Как уменьшить болезненность в области височно-нижнечелюстного сустава, если

При предполагаемом миогенном ВНЧС-расстройстве начните с обратимых консервативных мер: мягкая пища, кратковременный покой для челюсти при ос...

25 Jul 2026View Answer

<p>In a 34-year-old pregnant woman at 10 weeks’ gestation with a 3-week history

Most likely diagnosis: The presentation is most consistent with adult-onset Still’s disease (AOSD), with active systemic disease causing ser...

24 Jul 2026View Answer

<p>What is the expected reference range for serum human MMP-13 levels in adults

No validated reference range is available for serum human MMP-13 in adults with knee osteoarthritis from the supplied UK guidance or literat...

24 Jul 2026View Answer

<p>In a 51-year-old man who runs 5 km three times per week but is now limited

Working approach: Localise the dominant pain generator with a focused hip, groin/pelvic and lumbar neuromusculoskeletal assessment, while ac...

24 Jul 2026View Answer

What are the most effective types of exercise programmes for patients with low

Most effective types of exercise programmes for patients with low back pain include biomechanical, aerobic, mind–body, and combined approach...

22 Jul 2026View Answer

Can you suggest a patient self-management program for low back pain, including

Assessment: Start with a thorough assessment of the patient's low back pain, including the onset, type, site, pattern, pain radiation, durat...

22 Jul 2026View Answer

What are the red flag chief complaints that warrant immediate medical attention

Red flag chief complaints warranting immediate medical attention or urgent referral to the emergency room include the following:...

20 Jul 2026View Answer
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