clinical q&a library
Explore a database of clinical questions answered by iatroX, referencing established clinical guidelines, SmPCs, and peer-reviewed literature.
What management strategies should be considered for a patient diagnosed with cholestasis due to primary biliary cholangitis?
Management strategies for cholestasis due to primary biliary cholangitis (PBC) focus on slowing disease progression, managing symptoms, and monitorin...
Which imaging modalities are most effective in assessing the cause of cholestasis in primary care?
Ultrasound is the most effective and practical initial imaging modality in a primary care setting to assess the cause of cholestasis. It is ...
What initial investigations should I perform for a patient presenting with jaundice and suspected cholestasis?
Initial investigations for a patient presenting with jaundice and suspected cholestasis should include:Blood tests:...
When should I consider referring a patient with cholera for specialist care or hospitalization?
Consider referring a patient with cholera for specialist care or hospitalization if they show signs of clinical dehydration or shock, or if they have...
What preventive measures should be advised to patients traveling to areas with known cholera outbreaks?
Patients traveling to areas with known cholera outbreaks should be advised to strictly adhere to preventive measures focusing on safe water, food hygiene, an...
How should I manage a patient with suspected cholera who presents with severe dehydration?
Management of a patient with suspected cholera presenting with severe dehydration involves prompt and effective rehydration therapy.S...
What are the key clinical features to consider when diagnosing cholera in a patient presenting with acute diarrhoea?
Key clinical features to consider when diagnosing cholera in a patient presenting with acute diarrhoea include:Sudden onset of p...
What follow-up protocols should be in place for patients treated for cholangiocarcinoma to monitor for recurrence?
Follow-up protocols for patients treated for cholangiocarcinoma to monitor for disease recurrence are not explicitly detailed in the provided UK NICE...
How should I manage a patient with confirmed cholangiocarcinoma in terms of palliative care options?
Recommended palliative care options for a patient with confirmed cholangiocarcinoma focus on symptom management, improving quality of life, and addre...
What are the current guidelines for referring patients with suspected cholangiocarcinoma to specialist services?
Referral guidelines for suspected cholangiocarcinoma:Cholangiocarcinoma, a cancer of the bile ducts, is closely related to pancreatic...
Which imaging modalities are recommended for the diagnosis of cholangiocarcinoma in primary care settings?
In primary care settings, the recommended imaging modality for the initial assessment of suspected cholangiocarcinoma is an urgent, direct access ultrasound ...
What are the key clinical features and risk factors to consider when suspecting cholangiocarcinoma in a patient?
Key clinical features of cholangiocarcinoma typically include progressive painless jaundice, pruritus, dark urine, pale stools, and weight l...
How should I approach discussions with parents regarding their child's developmental progress and potential concerns?
Approach discussions with parents by first inviting them to share any concerns they have about their child's development. This helps to enga...
What tools or questionnaires are recommended for assessing child development in a primary care setting?
In a primary care setting, the recommended tools and questionnaires for assessing child development include the Parent Report of Children's Abilities – Revis...
What referral criteria should I consider for a child showing signs of significant developmental delay?
Consider referral to paediatric or specialist services for a child presenting with significant developmental delay if any of the following criteria are met:...
How can I effectively screen for developmental delays in preschool-aged children during consultations?
To effectively screen for developmental delays in preschool-aged children during consultations, use a combination of parent-completed questionnaires and dire...
What are the key developmental milestones for children aged 0-5 years that I should assess during routine check-ups?
During routine check-ups for children aged 0 to 5 years, key developmental milestones to assess include:Physical growth and measurements:...
Are there any specific investigations that should be conducted in patients with recurrent or severe chilblains?
In patients presenting with recurrent or severe chilblains, specific investigations should be considered to exclude underlying systemic or vascular c...
How can I assess the severity of ARDS in a patient and what implications does this have for treatment decisions?
To assess the severity of acute respiratory distress syndrome (ARDS) in a patient, clinicians should integrate clinical judgement with objective measures of ...