clinical q&a library
Explore a database of clinical questions answered by iatroX, referencing established clinical guidelines, SmPCs, and peer-reviewed literature.
How can I differentiate between functional dyspepsia and gastroesophageal reflux disease (GERD) in a patient presenting with upper gastrointestinal sy
Functional dyspepsia and gastroesophageal reflux disease (GERD) can be differentiated primarily based on symptom patterns a...
What are the key diagnostic criteria for Irritable Bowel Syndrome (IBS) according to the Rome IV guidelines?
The key diagnostic criteria for Irritable Bowel Syndrome (IBS) according to the Rome IV guidelines are:Presence of abdominal pai...
How should I approach the management of behavioral issues commonly associated with Fragile X Syndrome in my practice?
Approach to managing behavioral issues in Fragile X Syndrome (FXS) in clinical practice:Recognise that behavioral challenges ...
What are the recommended referral pathways for children diagnosed with Fragile X Syndrome for further support and management?
Children diagnosed with Fragile X Syndrome should be referred to multidisciplinary specialist services for comprehensive assessment and management due to the...
What genetic testing options are available for confirming a diagnosis of Fragile X Syndrome in suspected cases?
Genetic testing for confirming a diagnosis of Fragile X Syndrome (FXS) primarily involves analysis of the FMR1 gene to detect CGG trinucleotide repea...
How can I differentiate Fragile X Syndrome from other causes of intellectual disability in children?
Fragile X Syndrome (FXS) can be differentiated from other causes of intellectual disability in children primarily through its distinctive clinical fe...
What are the legal requirements for reporting deaths that may require forensic investigation?
In the UK, deaths that may require forensic investigation must be reported to the coroner without delay, particularly if the death is sudden, unexplained, or...
What role does forensic pathology play in cases of sudden unexplained death in young adults?
The role of forensic pathology in cases of sudden unexplained death in young adults is crucial for determining the cause of death and identifying pot...
How can I differentiate between accidental and non-accidental injuries in children during a routine examination?
During a routine examination, differentiate accidental from non-accidental injuries in children by carefully assessing the injury characteristics, explanatio...
What referral pathways exist for patients requiring forensic psychiatric assessment in primary care?
In primary care, patients requiring forensic psychiatric assessment should be referred to secondary care mental health services or specialist forensic servic...
What are the key considerations for a GP when assessing a patient with potential non-accidental injury?
Consider the child's appearance, behaviour, symptoms, physical signs, and results of investigations, as well as interactions between the child and ca...
When should I consider referring a patient with food poisoning to secondary care for further evaluation?
Consider referring a patient with food poisoning to secondary care for further evaluation if they present with any of the following:...
How should I manage a patient with suspected food poisoning who presents with severe dehydration?
Management of a patient with suspected food poisoning presenting with severe dehydration involves the following steps:As...
What role do elimination diets play in the diagnosis and management of food intolerances, and how should they be implemented?
Role of elimination diets: Elimination diets are used primarily in the diagnosis and management of non-IgE-mediated food allergies and intol...
What referral criteria should I consider for patients with suspected food intolerances who do not respond to initial dietary modifications?
Referral to secondary or specialist care should be considered for patients with suspected food intolerances who do not respond to initial dietary modificatio...
How should I approach dietary management for a patient diagnosed with lactose intolerance?
Approach dietary management for a patient diagnosed with lactose intolerance by first advising the patient to reduce or avoid lactose-containing foods to all...
Which diagnostic tests are recommended for evaluating suspected non-allergic food sensitivities in adults?
For evaluating suspected non-allergic food sensitivities (non-IgE-mediated food allergy) in adults, the recommended diagnostic approach is primarily clinical...
What are the key clinical features that differentiate food intolerance from food allergy in patients presenting with gastrointestinal symptoms?
Key clinical features differentiating food intolerance from food allergy in patients with gastrointestinal symptoms include the nature, timing, and s...
When should I consider referring a patient with folate deficiency for further investigation?
Consider referring a patient with folate deficiency for further investigation if:There is suspicion of an underlying cause that ...