guidelines

chronic cough in adults (≥8 weeks): structured assessment + referral

practical chronic cough pathway: red flags, targeted history/exam, baseline tests (cxr/spirometry), and common treatable causes.

last reviewed: 2026-02-13
based on: NICE CKS Cough and local respiratory referral pathways (accessed Feb 2026).

Executive summary

Define chronic cough as cough lasting ≥8 weeks. The key is to identify red flags, get a baseline assessment (often including CXR and spirometry), and treat common causes systematically (ACE-inhibitor cough, asthma/eosinophilic airway disease, upper airway cough syndrome, GORD).

Red flags (same-day or urgent imaging/referral)

  • Haemoptysis, weight loss, persistent fever/night sweats, significant breathlessness, chest pain, hoarseness, recurrent pneumonia.
  • Abnormal chest examination, new clubbing, supraclavicular nodes.
  • High-risk smoking history or occupational exposure.

Action: follow local suspected lung cancer pathways and arrange urgent CXR/CT as indicated; do not “trial and error” if red flags are present.

Baseline work-up (practical minimum)

  • Medication review: ACE inhibitor cough can occur weeks–months after starting; consider stopping and reassessing after ~4 weeks (if clinically safe).
  • Smoking/vaping status and occupational exposures.
  • Investigations: many pathways recommend CXR and spirometry (± bronchodilator reversibility) for cough persisting beyond a few weeks.

Common treatable causes (systematic trials)

  • Upper airway cough syndrome (post-nasal drip/rhinitis): nasal steroids + antihistamine if allergic features.
  • Asthma / eosinophilic airway disease: wheeze, variable symptoms; consider inhaled corticosteroid trial if supported by spirometry/FeNO/local pathway.
  • GORD: heartburn/regurgitation; lifestyle + PPI trial may help some patients, but avoid long PPI courses without review.
  • Chronic infection / bronchiectasis suspicion: daily sputum, recurrent infections → consider specialist referral.

Safety-net: if no improvement after sequential structured trials (and baseline tests), refer to respiratory clinic per local pathway.

FAQ

Transparency

This page is an educational, clinician-written summary of publicly available NICE guidance intended for trained healthcare professionals. It uses original wording (not copied text) and should be used alongside the full NICE source, local pathways, and clinical judgement. Doses provided are for general reference; always check the BNF/SPC.