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Recurrent miscarriage

A Canadian clinical summary of recurrent miscarriage, with source-attributed priorities and explicit jurisdiction boundaries.

JurisdictionCanada
Source check2026-08-20
Clinical reviewiatroX editorial team 路 Clinical editorial review 路 reviewed 2026-08-20 路 due 2027-08-20
AudienceHealthcare professionals practising in Canada
This is an iatroX educational summary of named Canada sources, not an official guideline. It does not replace the complete source documents, local policy, specialist advice or clinical judgement. The evidence source is pan-Canadian, but formularies, funded access, referral routes, public-health directions and service availability remain provincial or territorial.

Source and scope

This summary is bounded to the recommendations, population and decisions covered by Guideline No. 464: Recurrent Pregnancy Loss. Apply it with the current provincial or territorial pathway where implementation differs.
sources for this section:SOGC 464

Source-attributed clinical priorities

  • Confirm the pregnancy history and gestational timing and offer a structured evaluation for uterine, genetic, endocrine and antiphospholipid causes.
  • Avoid unsupported immune, thrombophilia or hormonal testing outside defined indications.
  • Provide prognosis, psychological support and an early-pregnancy plan, with treatment targeted to an identified cause.
  • Use a consistent definition and verify prior pregnancy records where possible before ordering an extensive workup.
sources for this section:SOGC 464

Practical assessment and management workflow

1
Document gestational age, ultrasound or pathology, live births, thrombosis, uterine procedures and family history.
2
Assess uterine anatomy, antiphospholipid antibodies and selected endocrine or genetic factors according to indication.
3
Explain the chance of future live birth and avoid unsupported tests and immune treatments.
4
Create an early-pregnancy contact, ultrasound and symptom plan and offer psychological support.
sources for this section:SOGC 464

Safety, red flags and urgent escalation

  • Heavy bleeding, syncope, severe pain or fever in a current pregnancy requires urgent assessment.
  • Do not prescribe aspirin or anticoagulation without an evidence-based indication.
  • Review parental karyotype or genetic testing through counselling when pregnancy-tissue findings or history warrants it.
sources for this section:SOGC 464

Confirm the local pathway before acting

The evidence source is pan-Canadian, but formularies, funded access, referral routes, public-health directions and service availability remain provincial or territorial.
sources for this section:SOGC 464

Source and implementation boundary

Read this educational summary with the linked source, current Canadian product information where medicines are involved, and the applicable provincial or territorial pathway. Local formularies, reporting duties, referral routes and service availability can differ.
sources for this section:SOGC 464

Source documents

Use the linked source documents for complete recommendations, evidence grading, exclusions and implementation detail.

  1. Society of Obstetricians and Gynaecologists of CanadaGuideline No. 464: Recurrent Pregnancy Lossaccessed 2026-08-20
    view source
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