Scope
The Bottom Line
- Estimate clinical probability before selecting D-dimer or imaging; a test result must be interpreted within a coherent DVT or pulmonary-embolism pathway.
- Ask about unilateral leg symptoms, previous VTE, immobility, surgery, cancer, pregnancy or postpartum status, oestrogen exposure and other provoking factors.
- Suspected DVT requires timely medical consultation because an untreated proximal clot can embolise; suspected PE requires respiratory and haemodynamic assessment at first contact.
- Anticoagulation choice and duration require the national guidance, current product information and individual bleeding, kidney, pregnancy and recurrence assessment.
Practical clinical workflow
Safety boundaries and escalation
- Hypotension, hypoxaemia, syncope, severe respiratory distress or suspected massive pulmonary embolism requires immediate emergency and retrieval escalation.
- Do not start, withhold or reverse anticoagulation without checking active bleeding, pregnancy, kidney function, interactions and the current local protocol.
Implementation
Clinical use boundary
This independently written summary is not an official guideline. Check the linked source version, current TGA-approved product information where medicines are involved, and the applicable state, territory and local pathway at the point of care.
Source documents
Use the linked source documents for complete recommendations, evidence grading, exclusions and implementation detail.
- Thrombosis and Haemostasis Society of Australia and New ZealandDiagnosis and management of venous thromboembolism: clinical guidanceDOI 10.5694/mja2.50004 · 2019 evidence-based guideline · accessed 2026-08-20view source
- Queensland Health and Royal Flying Doctor Service Queensland SectionPrimary Clinical Care Manual, 12th edition: Deep vein thrombosis and pulmonary embolismISBN 978-1-876560-22-5; Deep vein thrombosis and pulmonary embolism, pp. 119–121 · 12th edition 2025, v1.03 with updates through 21 July 2026; exact chapter at printed pages 119–121 · accessed 2026-08-20view source
From guidance to deliberate practice and evidence
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