Scope
The Bottom Line
- Consider sepsis in any acute illness or deterioration where infection is possible, including atypical hypothermia, delirium or falls in an older person.
- Obtain complete observations and assess mental state, perfusion, urine output and organ dysfunction; no single score or normal temperature excludes sepsis.
- Obtain blood cultures before antimicrobials when this causes no material delay and collect source specimens under the local bundle.
- Begin time-critical care under the local sepsis pathway, including source assessment, appropriate cultures and antimicrobials without avoidable diagnostic delay.
Practical clinical workflow
Topic-specific assessment action
Topic-specific diagnostic action
Topic-specific management action
Topic-specific follow-through
Safety boundaries and escalation
- Children, pregnancy and postpartum care need age- or maternity-specific tools and early expert escalation because presentation and physiology differ.
- At discharge after sepsis, reconcile medicines and arrange recovery, functional and infection-source follow-up because readmission risk remains elevated.
Implementation
Clinical use boundary
This independently written summary is not an official guideline. Check the linked source version, current TGA-approved product information where medicines are involved, and the applicable state, territory and local pathway at the point of care.
Source documents
Use the linked source documents for complete recommendations, evidence grading, exclusions and implementation detail.
- Australian Commission on Safety and Quality in Health CareSepsis Clinical Care Standard2022 standard 路 accessed 2026-08-20view source
From guidance to deliberate practice and evidence
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