Scope
The Bottom Line
- Confirm the timing and pattern after SARS-CoV-2 while considering reinfection and alternative cardiopulmonary, neurological, endocrine and mental-health diagnoses.
- Assess fatigue, post-exertional symptom exacerbation, breathlessness, chest symptoms, cognition, autonomic symptoms, sleep and functional or occupational impact.
- Use lying and standing measurements when orthostatic intolerance is reported and support fluid or compression advice only after contraindication review.
- Use symptom-directed examination and tests rather than a fixed investigation panel, and identify rehabilitation that will not provoke post-exertional deterioration.
Practical clinical workflow
Topic-specific assessment action
Topic-specific diagnostic action
Topic-specific management action
Topic-specific follow-through
Safety boundaries and escalation
- Urgently assess new hypoxia, chest pain, syncope, focal neurology, severe mental-health risk, thromboembolism or another acute deterioration rather than attributing it to long COVID.
- Avoid attributing all distress to anxiety; mental-health treatment and investigation of physical symptoms can proceed together.
Implementation
Clinical use boundary
This independently written summary is not an official guideline. Check the linked source version, current TGA-approved product information where medicines are involved, and the applicable state, territory and local pathway at the point of care.
Source documents
Use the linked source documents for complete recommendations, evidence grading, exclusions and implementation detail.
- NSW Agency for Clinical InnovationClinical practice guide for assessment and management of adults, children and young people with symptoms of long COVID2026 clinical practice guide 路 accessed 2026-08-20view source
From guidance to deliberate practice and evidence
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