Scope
The Bottom Line
- Confirm iron deficiency with ferritin interpreted alongside inflammation and assess haemoglobin severity, indices, reticulocytes and previous trend.
- Seek a cause through menstrual, gastrointestinal, dietary, blood donation, pregnancy, malabsorption and medicine history rather than treating indefinitely without explanation.
- Take oral iron away from inhibitors when tolerated, but prioritize a regimen the person can adhere to over maximal theoretical absorption.
- Adults without an obvious benign explanation may need coeliac testing and age- and risk-appropriate gastrointestinal investigation for occult bleeding or cancer.
Practical clinical workflow
Topic-specific assessment action
Topic-specific diagnostic action
Topic-specific management action
Topic-specific follow-through
Safety boundaries and escalation
- Haemodynamic instability, chest pain, syncope, active bleeding, severe breathlessness or failure to respond as expected requires urgent escalation or haematology advice.
- In heart failure or inflammatory bowel disease, intravenous iron decisions use disease-specific criteria rather than ferritin alone.
Implementation
Clinical use boundary
This independently written summary is not an official guideline. Check the linked source version, current TGA-approved product information where medicines are involved, and the applicable state, territory and local pathway at the point of care.
Source documents
Use the linked source documents for complete recommendations, evidence grading, exclusions and implementation detail.
- National Blood Authority AustraliaPatient Blood Management Guidelines: Module 3 — MedicalMedical module; exact NBA-hosted edition checked 2026-08-20 · accessed 2026-08-20view source
From guidance to deliberate practice and evidence
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