Scope
The Bottom Line
- Recognise acute illness involving airway, breathing or circulation, with or without skin signs, after a likely trigger as anaphylaxis requiring immediate treatment.
- Give intramuscular adrenaline into the outer mid-thigh without delay and repeat under the ASCIA protocol when response is inadequate.
- For people who are pregnant, position with left lateral tilt while maintaining standard adrenaline treatment.
- Position the person appropriately, avoid sudden standing, call emergency services and support airway, breathing and circulation; antihistamines do not treat shock.
Practical clinical workflow
Topic-specific assessment action
Topic-specific diagnostic action
Topic-specific management action
Topic-specific follow-through
Safety boundaries and escalation
- Refer for allergy evaluation and advise trigger avoidance, but do not delay emergency adrenaline while seeking diagnostic certainty or intravenous access.
- Record the event in the medical record and teach injector carriage and technique with a trainer device before discharge.
Implementation
Clinical use boundary
This independently written summary is not an official guideline. Check the linked source version, current TGA-approved product information where medicines are involved, and the applicable state, territory and local pathway at the point of care.
Source documents
Use the linked source documents for complete recommendations, evidence grading, exclusions and implementation detail.
- Australasian Society of Clinical Immunology and AllergyASCIA Guidelines: Acute management of anaphylaxisJuly 2026 guideline; current page checked 2026-08-20 路 accessed 2026-08-20view source
From guidance to deliberate practice and evidence
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