When should I consider referring a patient with SBP to secondary care for further management?

Guideline-aligned answer with reasoning, red flags and references. Clinically reviewed by Dr Kola Tytler MBBS CertHE MBA MRCGP.

Posted: 17 August 2025Updated: 17 August 2025 Guideline-Aligned (High Confidence) Clinically Reviewed
Dr Kola Tytler MBBS CertHE MBA MRCGPClinical Lead • iatroX

You should consider referring a patient with suspected spontaneous bacterial peritonitis (SBP) to secondary care for further management if they show signs of decompensated liver disease . Suspected SBP is a serious complication of cirrhosis and indicates decompensation .

Specifically, you should arrange emergency hospital admission or an immediate referral to a hepatologist or gastroenterologist with an interest in hepatology, based on clinical judgement .

Specialist treatment with prophylactic antibiotics to prevent SBP may also be considered for individuals with ascites who are at high risk of infection, or where the consequences of infection could severely impact their outcome and care .

Educational content only. Always verify information and use clinical judgement.