A 55-year-old man on ICU with hospital-acquired pneumonia is on IV linezolid day 12. Platelets drop from 180 to 65. What is the most likely cause?...

Question

A 55-year-old man on ICU with hospital-acquired pneumonia is on IV linezolid day 12. Platelets drop from 180 to 65. What is the most likely cause?

Accepted Answer

Linezolid-induced thrombocytopenia - occurring in approximately 20-30% of patients on linezolid for more than 10 days; it is dose and duration dependent and typically resolves within 5-7 days of cessation

Answer

HIT

Answer

DIC

Answer

Bone marrow infiltration

Answer

Vitamin B12 deficiency

uk-fficm MCQ (SBA): Linezolid Thrombocytopenia

A 55-year-old man on ICU with hospital-acquired pneumonia is on IV linezolid day 12. Platelets drop from 180 to 65. What is the most likely cause?