A 55-year-old man on ICU with sepsis-associated DIC has bleeding from multiple sites. His results show: platelets 22 × 10⁹/L, PT 28 seconds, fibrinoge...

Question

A 55-year-old man on ICU with sepsis-associated DIC has bleeding from multiple sites. His results show: platelets 22 × 10⁹/L, PT 28 seconds, fibrinogen 0.6 g/L, D-dimer >20,000 ng/mL. The ISTH DIC score is 7 (compatible with overt DIC). He is receiving cryoprecipitate. What fibrinogen target should be maintained?

Accepted Answer

Fibrinogen >1.0 g/L - some guidelines suggest >1.5 g/L for actively bleeding patients with DIC

Answer

Fibrinogen >0.5 g/L

Answer

Fibrinogen >3.0 g/L

Answer

Fibrinogen level does not matter in DIC

Answer

Fibrinogen >5.0 g/L

uk-fficm MCQ (SBA): DIC - Fibrinogen Target