A 50-year-old woman on ICU has distributive shock from pancreatitis. She is on noradrenaline 0.4 mcg/kg/min. Her lactate is 3.5 mmol/L and falling. MA...

Question

A 50-year-old woman on ICU has distributive shock from pancreatitis. She is on noradrenaline 0.4 mcg/kg/min. Her lactate is 3.5 mmol/L and falling. MAP is 68 mmHg. The team plans to wean the noradrenaline. What is the generally recommended approach to vasopressor weaning?

Accepted Answer

Gradually reduce the noradrenaline infusion rate in small decrements (e.g. 0.02-0.05 mcg/kg/min every 15-30 minutes), monitoring MAP and clinical perfusion markers at each step; aim for the lowest dose maintaining MAP ≥65 mmHg

Answer

Stop noradrenaline abruptly once MAP >65

Answer

Switch to oral vasopressor

Answer

Double the rate then stop

Answer

Vasopressor weaning requires no monitoring

uk-fficm MCQ (SBA): Vasopressor Weaning

A 50-year-old woman on ICU has distributive shock from pancreatitis. She is on noradrenaline 0.4 mcg/kg/min. Her lactate is 3.5 mmol/L and falling. MAP is 68 mmHg. The team plans to wean the noradrenaline. What is the generally recommended approach to vasopressor weaning?