Question

A 35-year-old man presents with 6 weeks of bloody diarrhoea, urgency, and tenesmus. Colonoscopy confirms extensive ulcerative colitis. He is systemically well with normal inflammatory markers. What is the most appropriate initial treatment?

Accepted Answer

High-dose oral Mesalazine

Answer

Oral Prednisolone 40 mg alone

Answer

Azathioprine monotherapy

Answer

Biologic therapy with Infliximab

Answer

No treatment is required

Practice question

A 35-year-old man presents with 6 weeks of bloody diarrhoea, urgency, and tenesmus. Colonoscopy confirms extensive ulcerative colitis. He is systemically well with normal inflammatory markers. What is the most appropriate initial treatment?