Question

A patient on regular modified-release oral morphine 60 mg twice daily for cancer pain reports intermittent breakthrough pain. What is the most appropriate dose of immediate-release morphine for breakthrough episodes?

Accepted Answer

One-sixth to one-tenth of the total 24-hour dose as needed

Answer

The same as the total 24-hour dose each time

Answer

No breakthrough dose is needed

Answer

Twice the total 24-hour dose as needed

Answer

Breakthrough dosing is not recommended with modified-release morphine

Practice question

A patient on regular modified-release oral morphine 60 mg twice daily for cancer pain reports intermittent breakthrough pain. What is the most appropriate dose of immediate-release morphine for breakthrough episodes?