Question

A 56-year-old man presents with a hot, swollen, exquisitely tender first metatarsophalangeal joint. He has a history of hypertension and chronic kidney disease stage 3. What is the most appropriate initial pharmacological treatment?

Accepted Answer

Colchicine at an appropriate dose

Answer

High-dose NSAIDs without consideration of renal function

Answer

Long-term Allopurinol started during the acute attack

Answer

Oral Prednisolone is contraindicated

Answer

Aspirin 75 mg daily

Practice question

A 56-year-old man presents with a hot, swollen, exquisitely tender first metatarsophalangeal joint. He has a history of hypertension and chronic kidney disease stage 3. What is the most appropriate initial pharmacological treatment?