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ModerateCardiovascularPrimary hypertension – initial drug choiceuk-plab-1

A 48-year-old man of Afro-Caribbean family origin has newly diagnosed uncomplicated primary hypertension with a clinic blood pressure of 165/100 mmHg confirmed on ABPM. He has no diabetes or kidney disease. According to NICE guidance, which is the single most appropriate first-line antihypertensive agent?

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