Question

A 72-year-old woman with atrial fibrillation and hypertension develops sudden onset unilateral leg swelling and pain after a long-haul flight. Doppler ultrasound confirms a proximal deep vein thrombosis. She has normal renal function. What is the most appropriate initial anticoagulation strategy?

Accepted Answer

Start a direct oral anticoagulant at treatment dose

Answer

Start Aspirin 75 mg daily

Answer

Start prophylactic-dose low molecular weight heparin

Answer

No anticoagulation is required if symptoms are mild

Answer

Use warfarin alone without initial parenteral or DOAC cover

Practice question

A 72-year-old woman with atrial fibrillation and hypertension develops sudden onset unilateral leg swelling and pain after a long-haul flight. Doppler ultrasound confirms a proximal deep vein thrombosis. She has normal renal function. What is the most appropriate initial anticoagulation strategy?