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ModerateEmergencyAcute severe asthmauk-plab-1

A 26-year-old woman with known asthma presents with increasing breathlessness and wheeze. She is unable to complete sentences. Observations: respiratory rate 30/min, pulse 120 bpm, oxygen saturation 93% on air, peak expiratory flow 40% of predicted. What is the single most appropriate immediate management?

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