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ModerateRespiratoryAcute exacerbation of COPDuk-plab-1

A 65 year old man with a history of chronic obstructive pulmonary disease presents with increasing breathlessness and productive cough for 3 days. He is using his short acting bronchodilator every 2 hours. On examination his respiratory rate is 28 breaths per minute, oxygen saturation is 89 percent on air, and there are widespread wheezes. Arterial blood gas on 28 percent oxygen shows pH 7.35, PaCO2 6.8 kPa and PaO2 7.8 kPa. What is the most appropriate initial oxygen target saturation range for this patient?

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