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ModerateInfectious DiseasesClostridioides difficile colitisuk-plab-1

A 75-year-old woman develops watery diarrhoea six times per day after a course of Co-amoxiclav. Stool testing is positive for Clostridioides difficile toxin. She is febrile at 38 degrees Celsius but haemodynamically stable and creatinine is normal. What is the most appropriate first-line treatment?

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