Question

A 58-year-old woman with a history of hypertension is started on an ACE inhibitor for newly diagnosed CKD and albuminuria. According to NICE guidance, what change in serum creatinine is acceptable after starting ACE inhibitor therapy before considering stopping the drug?

Accepted Answer

An increase in serum creatinine of up to 30% from baseline

Answer

Any increase is unacceptable and the drug must be stopped

Answer

Only a decrease is acceptable

Answer

A doubling of serum creatinine is acceptable

Answer

Creatinine is not monitored after starting ACE inhibitors

Practice question

A 58-year-old woman with a history of hypertension is started on an ACE inhibitor for newly diagnosed CKD and albuminuria. According to NICE guidance, what change in serum creatinine is acceptable after starting ACE inhibitor therapy before considering stopping the drug?