Question

A 72-year-old man with stage 3b chronic kidney disease (eGFR 34 mL/min/1.73 m²) and albumin:creatinine ratio 20 mg/mmol is on maximal dose ACE inhibitor. According to NICE guidance, which additional drug class should be considered to slow progression of kidney disease?

Accepted Answer

Add an SGLT2 inhibitor in addition to the ACE inhibitor

Answer

Stop ACE inhibitor and start a thiazide diuretic

Answer

No additional therapy is indicated

Answer

Start long-term NSAID therapy for analgesia

Answer

Aim to increase protein intake to 1.5 g/kg/day

Practice question

A 72-year-old man with stage 3b chronic kidney disease (eGFR 34 mL/min/1.73 m²) and albumin:creatinine ratio 20 mg/mmol is on maximal dose ACE inhibitor. According to NICE guidance, which additional drug class should be considered to slow progression of kidney disease?