ModerateCardiovascularHeart failure with reduced ejection fractionuk-plab-1
A 72-year-old man with a history of myocardial infarction and reduced left ventricular ejection fraction (35%) presents with exertional breathlessness and ankle swelling. He is in sinus rhythm and currently takes only Aspirin and Simvastatin. Blood pressure is 130/78 mmHg and renal function is normal. What is the most appropriate first-line disease-modifying treatment to add?