Question

A 58-year-old man with CKD stage 4 (eGFR 24 mL/min/1.73 m²) and type 2 diabetes is taking metformin 1 g twice daily. According to BNF and UK guidance, what should be done regarding his metformin?

Accepted Answer

Stop metformin as it is contraindicated at this level of eGFR

Answer

Continue at the same dose without change

Answer

Increase the dose to improve glycaemic control

Answer

Reduce the dose but continue indefinitely

Answer

Switch to insulin only if lactic acidosis develops

Practice question

A 58-year-old man with CKD stage 4 (eGFR 24 mL/min/1.73 m²) and type 2 diabetes is taking metformin 1 g twice daily. According to BNF and UK guidance, what should be done regarding his metformin?