Question

A 35-year-old woman with known IgA nephropathy presents with ankle oedema and blood pressure 150/95 mmHg. Urine dipstick shows 3+ protein and 2+ blood. eGFR is 80 mL/min/1.73 m². What is the most important pharmacological measure to slow progression of her kidney disease?

Accepted Answer

Start an ACE inhibitor even if creatinine rises slightly

Answer

Strict salt restriction alone

Answer

Avoid ACE inhibitors because of risk to renal function

Answer

Start high-dose loop diuretics

Answer

Use NSAIDs regularly for pain relief

Practice question

A 35-year-old woman with known IgA nephropathy presents with ankle oedema and blood pressure 150/95 mmHg. Urine dipstick shows 3+ protein and 2+ blood. eGFR is 80 mL/min/1.73 m². What is the most important pharmacological measure to slow progression of her kidney disease?