ModerateRenal/UrologyCKD with albuminuria – ACE inhibitor useuk-plab-1
A 60-year-old man with known diabetic nephropathy and hypertension has a urine albumin:creatinine ratio (ACR) of 45 mg/mmol and eGFR 50 mL/min/1.73 m². His blood pressure is 145/90 mmHg on Amlodipine alone. What is the most appropriate change to his antihypertensive therapy?