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ModerateRespiratoryAcute COPD exacerbationuk-plab-1

A 70-year-old man with known COPD (FEV1 40% predicted) presents with an infective exacerbation. On air his saturations are 84%, respiratory rate 28 breaths/min, and he is drowsy. Arterial blood gases show pH 7.30, PaCO2 8.0 kPa, PaO2 6.5 kPa. What target oxygen saturation range should be used initially?

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