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HardHaematologyNeutropenic sepsisuk-plab-1

A 58-year-old man with lateral knee replacement 7 days ago presents with fever and rigors. He looks unwell, BP 92/58 mmHg, pulse 124 bpm, temperature 38.9°C. He had chemotherapy 5 days ago for lymphoma; current neutrophil count is 0.3 × 10⁹/L. What is the most appropriate immediate management?

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