Question

A 70-year-old man with known metastatic prostate cancer is bedbound and has severe agitation and delirium in the last days of life, despite optimised analgesia. What is the most appropriate pharmacological management of his terminal agitation?

Accepted Answer

Regular subcutaneous Haloperidol or Midazolam via syringe driver

Answer

High-dose Diazepam orally

Answer

Increase opioid dose only

Answer

Start high-dose steroids

Answer

Use antipsychotics only if he becomes violent

Practice question

A 70-year-old man with known metastatic prostate cancer is bedbound and has severe agitation and delirium in the last days of life, despite optimised analgesia. What is the most appropriate pharmacological management of his terminal agitation?