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ModerateCardiovascularPrimary hypertensionuk-plab-1

A 58-year-old man with a history of hypertension presents to his GP. His clinic blood pressure on two occasions is 160/96 mmHg. Ambulatory blood pressure monitoring confirms an average daytime BP of 158/94 mmHg. He has no target organ damage and no diabetes or cardiovascular disease. What is the most appropriate first-line drug treatment?

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