Question

A 65-year-old man with non-valvular atrial fibrillation is commencing apixaban for stroke prevention. His eGFR is 40 mL/min/1.73 m2 and weight 60 kg. According to the Australian Medicines Handbook, which factor does NOT contribute to dose reduction for apixaban in atrial fibrillation?

Accepted Answer

History of prior stroke or TIA

Answer

Age ≥80 years

Answer

Body weight ≤60 kg

Answer

Serum creatinine ≥133 µmol/L

Answer

Concurrent use of verapamil

Practice question

A 65-year-old man with non-valvular atrial fibrillation is commencing apixaban for stroke prevention. His eGFR is 40 mL/min/1.73 m2 and weight 60 kg. According to the Australian Medicines Handbook, which factor does NOT contribute to dose reduction for apixaban in atrial fibrillation?