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MediumInfectious DiseasesAcute pyelonephritis and sepsisau-amcau-acemau-racp

A 67-year-old woman presents with fever, flank pain and rigors. She is hypotensive (BP 90/50 mmHg), tachycardic and has costovertebral angle tenderness. Urinalysis shows nitrites and leukocytes. What is the most appropriate management?

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